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Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production
Staphylococcus aureus is a foremost bacterial pathogen responsible for a vast array of human diseases. Staphylococcal superantigens (SAgs) constitute a family of exotoxins from S. aureus that bind directly to major histocompatibility complex (MHC) class II and T cell receptors to drive extensive T c...
Autores principales: | Tuffs, Stephen W., Goncheva, Mariya I., Xu, Stacey X., Craig, Heather C., Kasper, Katherine J., Choi, Joshua, Flannagan, Ronald S., Kerfoot, Steven M., Heinrichs, David E., McCormick, John K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872782/ https://www.ncbi.nlm.nih.gov/pubmed/35165181 http://dx.doi.org/10.1073/pnas.2115987119 |
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