Trafficking-defective mutant PROKR2 cycles between endoplasmic reticulum and Golgi to attenuate endoplasmic reticulum stress

G protein–coupled receptors (GPCRs) play crucial roles in numerous physiological and pathological processes. Mutations in GPCRs that result in loss of function or alterations in signaling can lead to inherited or acquired diseases. Herein, studying prokineticin receptor 2 (PROKR2), we initially iden...

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Detalles Bibliográficos
Autores principales: Song, Yong Bhum, Park, Seung-Yeol, Park, Kunyou, Hwang, Hayoung, Carroll, Rona S., Hsu, Victor W., Kaiser, Ursula B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872787/
https://www.ncbi.nlm.nih.gov/pubmed/35173048
http://dx.doi.org/10.1073/pnas.2102248119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872787/
https://www.ncbi.nlm.nih.gov/pubmed/35173048
http://dx.doi.org/10.1073/pnas.2102248119

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