Mycobacterium tuberculosis DNA repair helicase UvrD1 is activated by redox-dependent dimerization via a 2B domain cysteine

Mycobacterium tuberculosis (Mtb) causes tuberculosis and, during infection, is exposed to reactive oxygen species and reactive nitrogen intermediates from the host immune response that can cause DNA damage. UvrD-like proteins are involved in DNA repair and replication and belong to the SF1 family of...

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Detalles Bibliográficos
Autores principales: Chadda, Ankita, Jensen, Drake, Tomko, Eric J., Ruiz Manzano, Ana, Nguyen, Binh, Lohman, Timothy M., Galburt, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872793/
https://www.ncbi.nlm.nih.gov/pubmed/35173050
http://dx.doi.org/10.1073/pnas.2114501119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872793/
https://www.ncbi.nlm.nih.gov/pubmed/35173050
http://dx.doi.org/10.1073/pnas.2114501119

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