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Light-guided intrabodies for on-demand in situ target recognition in human cells
Due to their high stability and specificity in living cells, fluorescently labeled nanobodies are perfect probes for visualizing intracellular targets at an endogenous level. However, intrabodies bind unrestrainedly and hence may interfere with the target protein function. Here, we report a strategy...
Autores principales: | Joest, Eike F., Winter, Christian, Wesalo, Joshua S., Deiters, Alexander, Tampé, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872839/ https://www.ncbi.nlm.nih.gov/pubmed/35342543 http://dx.doi.org/10.1039/d1sc01331a |
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