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Modifying the m(6)A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging

Synaptic plasticity processes, which underlie learning and memory formation, require RNA to be translated local to synapses. The synaptic tagging hypothesis has previously been proposed to explain how mRNAs are available at specific activated synapses. However how RNA is regulated, and which transcr...

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Detalles Bibliográficos
Autores principales: Martinez De La Cruz, Braulio, Markus, Robert, Malla, Sunir, Haig, Maria Isabel, Gell, Chris, Sang, Fei, Bellows, Eleanor, Sherif, Mahmoud Awad, McLean, Denise, Lourdusamy, Anbarasu, Self, Tim, Bodi, Zsuzsanna, Smith, Stuart, Fay, Michael, Macdonald, Ian A., Fray, Rupert, Knight, Helen Miranda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872986/
https://www.ncbi.nlm.nih.gov/pubmed/34663904
http://dx.doi.org/10.1038/s41380-021-01282-z