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Autoantibodies against NMDA receptor 1 modify rather than cause encephalitis

The etiology and pathogenesis of “anti-N-methyl-D-aspartate-receptor (NMDAR) encephalitis” and the role of autoantibodies (AB) in this condition are still obscure. While NMDAR1-AB exert NMDAR-antagonistic properties by receptor internalization, no firm evidence exists to date that NMDAR1-AB by thems...

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Detalles Bibliográficos
Autores principales: Wilke, Justus B. H., Hindermann, Martin, Berghoff, Stefan A., Zihsler, Svenja, Arinrad, Sahab, Ronnenberg, Anja, Barnkothe, Nadine, Steixner-Kumar, Agnes A., Röglin, Stefan, Stöcker, Winfried, Hollmann, Michael, Nave, Klaus-Armin, Lühder, Fred, Ehrenreich, Hannelore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872987/
https://www.ncbi.nlm.nih.gov/pubmed/34331009
http://dx.doi.org/10.1038/s41380-021-01238-3