Inhibitory effects on L- and N-type calcium channels by a novel Ca(V)β(1) variant identified in a patient with autism spectrum disorder

Voltage-gated calcium channel (VGCC) subunits have been genetically associated with autism spectrum disorders (ASD). The properties of the pore-forming VGCC subunit are modulated by auxiliary β-subunits, which exist in four isoforms (Ca(V)β(1-4)). Our previous findings suggested that activation of L...

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Detalles Bibliográficos
Autores principales: Despang, Patrick, Salamon, Sarah, Breitenkamp, Alexandra, Kuzmenkina, Elza, Matthes, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873119/
https://www.ncbi.nlm.nih.gov/pubmed/35122502
http://dx.doi.org/10.1007/s00210-022-02213-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873119/
https://www.ncbi.nlm.nih.gov/pubmed/35122502
http://dx.doi.org/10.1007/s00210-022-02213-7

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