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Meningitic Escherichia coli-Induced Interleukin-17A Facilitates Blood–Brain Barrier Disruption via Inhibiting Proteinase 3/Protease-Activated Receptor 2 Axis

Bacterial meningitis is a life-threatening infectious disease with high morbidity and mortality worldwide, among which meningitic Escherichia coli is a common Gram-negative pathogenic bacterium causing meningitis. It can penetrate the blood–brain barrier (BBB), invoke local inflammatory responses an...

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Detalles Bibliográficos
Autores principales: Xu, Bojie, Chen, Jiaqi, Fu, Jiyang, Yang, Ruicheng, Yang, Bo, Huo, Dong, Tan, Chen, Chen, Huanchun, Wang, Xiangru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873187/
https://www.ncbi.nlm.nih.gov/pubmed/35221923
http://dx.doi.org/10.3389/fncel.2022.814867