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Meningitic Escherichia coli-Induced Interleukin-17A Facilitates Blood–Brain Barrier Disruption via Inhibiting Proteinase 3/Protease-Activated Receptor 2 Axis
Bacterial meningitis is a life-threatening infectious disease with high morbidity and mortality worldwide, among which meningitic Escherichia coli is a common Gram-negative pathogenic bacterium causing meningitis. It can penetrate the blood–brain barrier (BBB), invoke local inflammatory responses an...
Autores principales: | Xu, Bojie, Chen, Jiaqi, Fu, Jiyang, Yang, Ruicheng, Yang, Bo, Huo, Dong, Tan, Chen, Chen, Huanchun, Wang, Xiangru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873187/ https://www.ncbi.nlm.nih.gov/pubmed/35221923 http://dx.doi.org/10.3389/fncel.2022.814867 |
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