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Loss of chaperone-mediated autophagy is associated with low vertebral cancellous bone mass

Chaperone-mediated autophagy (CMA) is a protein degradation pathway that eliminates soluble cytoplasmic proteins that are damaged, incorrectly folded, or targeted for selective proteome remodeling. However, the role of CMA in skeletal homeostasis under physiological and pathophysiological conditions...

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Detalles Bibliográficos
Autores principales: Akel, Nisreen, MacLeod, Ryan S., Berryhill, Stuart B., Laster, Dominique J., Dimori, Milena, Crawford, Julie A., Fu, Qiang, Onal, Melda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873216/
https://www.ncbi.nlm.nih.gov/pubmed/35210514
http://dx.doi.org/10.1038/s41598-022-07157-9