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Loss of chaperone-mediated autophagy is associated with low vertebral cancellous bone mass
Chaperone-mediated autophagy (CMA) is a protein degradation pathway that eliminates soluble cytoplasmic proteins that are damaged, incorrectly folded, or targeted for selective proteome remodeling. However, the role of CMA in skeletal homeostasis under physiological and pathophysiological conditions...
Autores principales: | Akel, Nisreen, MacLeod, Ryan S., Berryhill, Stuart B., Laster, Dominique J., Dimori, Milena, Crawford, Julie A., Fu, Qiang, Onal, Melda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873216/ https://www.ncbi.nlm.nih.gov/pubmed/35210514 http://dx.doi.org/10.1038/s41598-022-07157-9 |
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