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In-depth comparison of the metabolic and pharmacokinetic behaviour of the structurally related synthetic cannabinoids AMB-FUBINACA and AMB-CHMICA in rats

Synthetic cannabinoids receptor agonists (SCRAs) are often almost completely metabolised, and hence their pharmacokinetics should be carefully evaluated for determining the most adequate biomarker in toxicological analysis. Two structurally related SCRAs, AMB-FUBINACA and AMB-CHMICA, were selected t...

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Detalles Bibliográficos
Autores principales: Fabregat-Safont, David, Mata-Pesquera, María, Barneo-Muñoz, Manuela, Martinez-Garcia, Ferran, Mardal, Marie, Davidsen, Anders B., Sancho, Juan V., Hernández, Félix, Ibáñez, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873228/
https://www.ncbi.nlm.nih.gov/pubmed/35210552
http://dx.doi.org/10.1038/s42003-022-03113-5