Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target to re-activate progenitors

Following the decline of neurogenesis at birth, progenitors of the subventricular zone (SVZ) remain mostly in a quiescent state in the adult human brain. The mechanisms that regulate this quiescent state are still unclear. Here, we isolate CD271(+) progenitors from the aged human SVZ for single-cell...

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Detalles Bibliográficos
Autores principales: Donega, Vanessa, van der Geest, Astrid T., Sluijs, Jacqueline A., van Dijk, Roland E., Wang, Chi Chiu, Basak, Onur, Pasterkamp, R. Jeroen, Hol, Elly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873234/
https://www.ncbi.nlm.nih.gov/pubmed/35210419
http://dx.doi.org/10.1038/s41467-022-28626-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873234/
https://www.ncbi.nlm.nih.gov/pubmed/35210419
http://dx.doi.org/10.1038/s41467-022-28626-9

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