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Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target to re-activate progenitors
Following the decline of neurogenesis at birth, progenitors of the subventricular zone (SVZ) remain mostly in a quiescent state in the adult human brain. The mechanisms that regulate this quiescent state are still unclear. Here, we isolate CD271(+) progenitors from the aged human SVZ for single-cell...
Autores principales: | Donega, Vanessa, van der Geest, Astrid T., Sluijs, Jacqueline A., van Dijk, Roland E., Wang, Chi Chiu, Basak, Onur, Pasterkamp, R. Jeroen, Hol, Elly M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873234/ https://www.ncbi.nlm.nih.gov/pubmed/35210419 http://dx.doi.org/10.1038/s41467-022-28626-9 |
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