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2‐Deoxy‐d‐glucose induces deglycosylation of proinflammatory cytokine receptors and strongly reduces immunological responses in mouse models of inflammation

Anti‐proinflammatory cytokine therapies against interleukin (IL)‐6, tumor necrosis factor (TNF)‐α, and IL‐1 are major advancements in treating inflammatory diseases, especially rheumatoid arthritis. Such therapies are mainly performed by injection of antibodies against cytokines or cytokine receptor...

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Detalles Bibliográficos
Autores principales: Uehara, Ikuno, Kajita, Mitsuko, Tanimura, Atsuko, Hida, Shigeaki, Onda, Munehiko, Naito, Zenya, Taki, Shinsuke, Tanaka, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873284/
https://www.ncbi.nlm.nih.gov/pubmed/35212163
http://dx.doi.org/10.1002/prp2.940