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SUMOylation of PDPK1 Is required to maintain glycolysis-dependent CD4 T-cell homeostasis
The immune system is finely tuned to fight against infections, eradicate neoplasms, and prevent autoimmunity. Protein posttranslational modification (PTM) constitutes a molecular layer of regulation to guarantee the proper intensity of immune response. Herein, we report that UBC9-mediated protein SU...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873481/ https://www.ncbi.nlm.nih.gov/pubmed/35210408 http://dx.doi.org/10.1038/s41419-022-04622-1 |