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PCLAF promotes neuroblastoma G1/S cell cycle progression via the E2F1/PTTG1 axis

PCLAF (PCNA clamp-associated factor), also known as PAF15/ KIAA0101, is overexpressed in most human cancers and is a predominant regulator of tumor progression. However, its biological function in neuroblastoma remains unclear. PCLAF is extremely overexpressed in neuroblastoma and is associated with...

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Detalles Bibliográficos
Autores principales: Liu, Xiaowei, Cai, Yuanxia, Cheng, Cheng, Gu, Yaoyao, Hu, Xiaoxiao, Chen, Kai, Wu, Yeming, Wu, Zhixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873510/
https://www.ncbi.nlm.nih.gov/pubmed/35210406
http://dx.doi.org/10.1038/s41419-022-04635-w