Targeted 1,3-dipolar cycloaddition with acrolein for cancer prodrug activation

Cytotoxic anticancer drugs used in chemotherapy are often antiproliferative agents that preferentially kill rapidly growing cancer cells. Their mechanism relies mainly on the enhanced proliferation rate of cancer cells and is not genuinely selective for cancer cells. Therefore, these drugs can also...

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Detalles Bibliográficos
Autores principales: Pradipta, Ambara R., Ahmadi, Peni, Terashima, Kazuki, Muguruma, Kyohei, Fujii, Motoko, Ichino, Tomoya, Maeda, Satoshi, Tanaka, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873552/
https://www.ncbi.nlm.nih.gov/pubmed/35340932
http://dx.doi.org/10.1039/d0sc06083f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873552/
https://www.ncbi.nlm.nih.gov/pubmed/35340932
http://dx.doi.org/10.1039/d0sc06083f

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