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M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway

Exosomes serve as a crucial mode of communication between tumor-associated macrophages (TAMs) and cancer cells. This study attempted to explore the function of M1-derived exosomes and clarify their specific mechanism in head and neck squamous cell carcinoma (HNSCC). Moreover, the functional roles of...

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Detalles Bibliográficos
Autores principales: Jiang, Huaili, Zhou, Lei, Shen, Na, Ning, Xianhui, Wu, Daquan, Jiang, Kanglun, Huang, Xinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873565/
https://www.ncbi.nlm.nih.gov/pubmed/35210436
http://dx.doi.org/10.1038/s41419-022-04640-z