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Bactericidal, anti-biofilm, and anti-virulence activity of vitamin C against carbapenem-resistant hypervirulent Klebsiella pneumoniae

The emergence of carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) causing high mortality in clinical patients infers the urgent need for developing therapeutic agents. Here, we demonstrated vitamin C (VC) exhibited strong bactericidal, anti-biofilm, and virulence-suppressing effect...

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Detalles Bibliográficos
Autores principales: Xu, Chen, Dong, Ning, Chen, Kaichao, Yang, Xuemei, Zeng, Ping, Hou, Changshun, Chi Chan, Edward Wai, Yao, Xi, Chen, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873610/
https://www.ncbi.nlm.nih.gov/pubmed/35243252
http://dx.doi.org/10.1016/j.isci.2022.103894