Metabolic Regulation of Macrophages by SIRT1 Determines Activation During Cholestatic Liver Disease in Mice

BACKGROUND & AIMS: Inflammation is the hallmark of chronic liver disease. Metabolism is a key determinant to regulate the activation of immune cells. Here, we define the role of sirtuin 1 (SIRT1), a main metabolic regulator, in controlling the activation of macrophages during cholestatic liver d...

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Detalles Bibliográficos
Autores principales: Isaacs-Ten, Anna, Moreno-Gonzalez, Mar, Bone, Caitlin, Martens, Andre, Bernuzzi, Federico, Ludwig, Tobias, Hellmich, Charlotte, Hiller, Karsten, Rushworth, Stuart A., Beraza, Naiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873616/
https://www.ncbi.nlm.nih.gov/pubmed/34952202
http://dx.doi.org/10.1016/j.jcmgh.2021.12.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873616/
https://www.ncbi.nlm.nih.gov/pubmed/34952202
http://dx.doi.org/10.1016/j.jcmgh.2021.12.010

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