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Protein Kinase CK2 Acts as a Molecular Brake to Control NADPH Oxidase 1 Activation and Colon Inflammation

BACKGROUND & AIMS: NADPH oxidase 1 (NOX1) has emerged as a prime regulator of intestinal mucosa immunity and homeostasis. Dysregulation of NOX1 may cause inflammatory bowel disease (IBD). It is not clear how NOX1 is regulated in vivo under inflammatory conditions. We studied the role of CK2 in t...

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Detalles Bibliográficos
Autores principales: Liu, Dan, Marie, Jean-Claude, Pelletier, Anne-Laure, Song, Zhuoyao, Ben-Khemis, Marwa, Boudiaf, Kaouthar, Pintard, Coralie, Leger, Thibaut, Terrier, Samuel, Chevreux, Guillaume, El-Benna, Jamel, Dang, Pham My-Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873962/
https://www.ncbi.nlm.nih.gov/pubmed/35031518
http://dx.doi.org/10.1016/j.jcmgh.2022.01.003