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Avasimibe Alleviates Disruption of the Airway Epithelial Barrier by Suppressing the Wnt/β-Catenin Signaling Pathway

Avasimibe (Ava) is an acetyl-CoA acetyltransferase 1 (ACAT1) specific inhibitor and an established medicine for atherosclerosis, owing to its excellent and safe anti-inflammation effects in humans. However, its efficacy in asthma has not yet been reported. We first administered varying concentration...

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Detalles Bibliográficos
Autores principales: Zhou, Zicong, Liang, Shixiu, Zhou, Zili, Liu, Jieyi, Meng, Xiaojing, Zou, Fei, Yu, Changhui, Cai, Shaoxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874122/
https://www.ncbi.nlm.nih.gov/pubmed/35222024
http://dx.doi.org/10.3389/fphar.2022.795934