Atorvastatin Restores PPARα Inhibition of Lipid Metabolism Disorders by Downregulating miR-21 Expression to Improve Mitochondrial Function and Alleviate Diabetic Nephropathy Progression

Atorvastatin is a classical lipid-lowering drug. It has been reported to have renoprotective effects, such as reducing urinary protein excretion and extracellular matrix aggregation. The present study aimed to investigate the specific mechanism of action of Atorvastatin in type 1 diabetic mice (T1DM...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiang, Jiayi, Zhang, Huifang, Zhou, Xingcheng, Wang, Dan, Chen, Rongyu, Tan, Wanlin, Liang, Luqun, Shi, Mingjun, Zhang, Fan, Xiao, Ying, Zhou, Yuxia, Wang, Yuanyuan, Guo, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874267/
https://www.ncbi.nlm.nih.gov/pubmed/35222033
http://dx.doi.org/10.3389/fphar.2022.819787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874267/
https://www.ncbi.nlm.nih.gov/pubmed/35222033
http://dx.doi.org/10.3389/fphar.2022.819787

Ejemplares similares