Elevated Levels of Soluble CTLA-4, PD-1, PD-L1, LAG-3 and TIM-3 and Systemic Inflammatory Stress as Potential Contributors to Immune Suppression and Generalized Tumorigenesis in a Cohort of South African Xeroderma Pigmentosum Patients

Xeroderma Pigmentosum (XP), an autosomal recessive disorder characterized by ultraviolet radiation-induced abnormalities of DNA excision and repair pathways is associated with early development of cutaneous cancers. Intracellular oxidative stress has also been proposed as a contributor to the occurr...

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Detalles Bibliográficos
Autores principales: Kgokolo, Mahlatse C. M., Anderson, Katherine, Siwele, Shalate C., Steel, Helen C., Kwofie, Luyanda L. I., Sathekge, Mike M., Meyer, Pieter W. A., Rapoport, Bernardo L., Anderson, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874270/
https://www.ncbi.nlm.nih.gov/pubmed/35223501
http://dx.doi.org/10.3389/fonc.2022.819790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874270/
https://www.ncbi.nlm.nih.gov/pubmed/35223501
http://dx.doi.org/10.3389/fonc.2022.819790

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