3, 3′- (3, 5-DCPBC) Down-Regulates Multiple Phosphokinase Dependent Signal Transduction Pathways in Malignant Melanoma Cells through Specific Diminution of EGFR(Y1086) Phosphorylation

Melanoma is the most dangerous skin malignancy due to its strong metastatic potential with high mortality. Activation of crucial signaling pathways enforcing melanoma progression depends on phosphorylation of distinct tyrosine kinases and oxidative stress. We here investigated the effect of a bis-co...

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Detalles Bibliográficos
Autores principales: Qurat-ul-Ain, Basu, Abhijit, Choudhary, M. Iqbal, Scharffetter-Kochanek, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874408/
https://www.ncbi.nlm.nih.gov/pubmed/35208960
http://dx.doi.org/10.3390/molecules27041172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874408/
https://www.ncbi.nlm.nih.gov/pubmed/35208960
http://dx.doi.org/10.3390/molecules27041172

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