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Biochemical and Structural Insights into the Winged Helix Domain of P150, the Largest Subunit of the Chromatin Assembly Factor 1

The Chromatin Assembly Factor 1 is a heterotrimeric complex responsible for the nucleosome assembly during DNA replication and DNA repair. In humans, the largest subunit P150 is the major actor of this process. It has been recently considered as a tumor-associated protein due to its overexpression i...

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Detalles Bibliográficos
Autores principales: Ayoub, Joëlle, Buonanno, Martina, Di Fiore, Anna, De Simone, Giuseppina, Monti, Simona Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874411/
https://www.ncbi.nlm.nih.gov/pubmed/35216276
http://dx.doi.org/10.3390/ijms23042160