Cargando…
Biochemical and Structural Insights into the Winged Helix Domain of P150, the Largest Subunit of the Chromatin Assembly Factor 1
The Chromatin Assembly Factor 1 is a heterotrimeric complex responsible for the nucleosome assembly during DNA replication and DNA repair. In humans, the largest subunit P150 is the major actor of this process. It has been recently considered as a tumor-associated protein due to its overexpression i...
Autores principales: | Ayoub, Joëlle, Buonanno, Martina, Di Fiore, Anna, De Simone, Giuseppina, Monti, Simona Maria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874411/ https://www.ncbi.nlm.nih.gov/pubmed/35216276 http://dx.doi.org/10.3390/ijms23042160 |
Ejemplares similares
-
The wing of the ToxR winged helix-turn-helix domain is required for DNA binding and activation of toxT and ompU
por: Morgan, Sarah J., et al.
Publicado: (2019) -
A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli
por: Smith, Corey L., et al.
Publicado: (2014) -
Chromatin assembly factor 1, subunit A (P150) facilitates cell proliferation in human hepatocellular carcinoma
por: Xu, Meng, et al.
Publicado: (2016) -
Biochemical, structural, and computational studies of a γ-carbonic
anhydrase from the pathogenic bacterium Burkholderia
pseudomallei
por: Di Fiore, Anna, et al.
Publicado: (2022) -
The SWI/SNF Subunit INI1 Contains an N-Terminal Winged Helix DNA Binding Domain that Is a Target for Mutations in Schwannomatosis
por: Allen, Mark D., et al.
Publicado: (2015)