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Influence of Steric Effect on the Pseudo-Multicomponent Synthesis of N-Aroylmethyl-4-Arylimidazoles

A pseudo-three-component synthesis of N-aroylmethylimidazoles 3 with three new C–N bonds formed regioselectively under microwave conditions was developed. Products were obtained by reacting two equivalents of aroylmethyl bromide (ArCOCH(2)Br, 1) with the appropriate amidine salt (RCN(2)H(3).HX, 2) a...

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Detalles Bibliográficos
Autores principales: Elejalde-Cadena, Nerith Rocio, García-Olave, Mayra, Figueroa, David, Vidossich, Pietro, Miscione, Gian Pietro, Portilla, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874432/
https://www.ncbi.nlm.nih.gov/pubmed/35208948
http://dx.doi.org/10.3390/molecules27041165