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Influence of Steric Effect on the Pseudo-Multicomponent Synthesis of N-Aroylmethyl-4-Arylimidazoles
A pseudo-three-component synthesis of N-aroylmethylimidazoles 3 with three new C–N bonds formed regioselectively under microwave conditions was developed. Products were obtained by reacting two equivalents of aroylmethyl bromide (ArCOCH(2)Br, 1) with the appropriate amidine salt (RCN(2)H(3).HX, 2) a...
Autores principales: | Elejalde-Cadena, Nerith Rocio, García-Olave, Mayra, Figueroa, David, Vidossich, Pietro, Miscione, Gian Pietro, Portilla, Jaime |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874432/ https://www.ncbi.nlm.nih.gov/pubmed/35208948 http://dx.doi.org/10.3390/molecules27041165 |
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