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Intracellular Survival of Biofilm-Forming MRSA OJ-1 by Escaping from the Lysosome and Autophagosome in J774A Cells Cultured in Overdosed Vancomycin

We investigated the drug-resistant mechanisms of intracellular survival of methicillin-resistant S. aureus (MRSA). Our established MRSA clinical strain, OJ-1, with high biofilm-forming ability, and a macrophage cell line, J774A, were used. After ingestion of OJ-1 by J774A, the cells were incubated f...

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Detalles Bibliográficos
Autores principales: Jimi, Shiro, Yoshimura, Michinobu, Mashima, Kota, Ueda, Yutaka, Miyazaki, Motoyasu, Saparov, Arman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874447/
https://www.ncbi.nlm.nih.gov/pubmed/35208802
http://dx.doi.org/10.3390/microorganisms10020348