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The Safety and Efficacy of Nusinersen in the Treatment of Spinal Muscular Atrophy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Background and objectives: Spinal muscular atrophy (SMA) is a neurodegenerative disease that leads to progressive proximal muscle weakness and muscle atrophy. To assess the beneficial and adverse effects of nusinersen, a promising intervention for SMA, we conducted a systematic search and meta-analy...

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Detalles Bibliográficos
Autores principales: Abbas, Kirellos Said, Eltaras, Mennatullah Mohamed, El-Shahat, Nahla Ahmed, Abdelazeem, Basel, Shaqfeh, Mahmoud, Brašić, James Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874456/
https://www.ncbi.nlm.nih.gov/pubmed/35208537
http://dx.doi.org/10.3390/medicina58020213