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PEGylated Chitosan Nanoparticles Encapsulating Ascorbic Acid and Oxaliplatin Exhibit Dramatic Apoptotic Effects against Breast Cancer Cells

This study aims to design a pH-responsive dual-loaded nanosystem based on PEGylated chitosan nanoparticles loaded with ascorbic acid (AA) and oxaliplatin (OX) for the effective treatment of breast cancer. In this regard, non-PEGylated and PEGylated chitosan nanoparticles (CS NPs) loaded with either...

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Detalles Bibliográficos
Autores principales: Fahmy, Sherif Ashraf, Ramzy, Asmaa, Mandour, Asmaa A., Nasr, Soad, Abdelnaser, Anwar, Bakowsky, Udo, Azzazy, Hassan Mohamed El-Said
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874531/
https://www.ncbi.nlm.nih.gov/pubmed/35214139
http://dx.doi.org/10.3390/pharmaceutics14020407