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Impact of IFN-γ Deficiency on the Cardiomyocyte Function in the First Stage of Experimental Chagas Disease

Chagas disease (CD) is caused by the parasitic protozoan T. cruzi. The progression of CD in ~30% of patients results in Chagasic Cardiomyopathy (CCM). Currently, it is known that the inflammatory system plays a significant role in the CCM. Interferon-gamma (IFN-γ) is the major cytokine involved in p...

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Detalles Bibliográficos
Autores principales: Roman-Campos, Danilo, Sales-Junior, Policarpo, Costa, Alexandre D., Souza, Diego Santos, Santos-Miranda, Artur, Joviano-Santos, Julliane V., Ropert, Catherine, Cruz, Jader S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874532/
https://www.ncbi.nlm.nih.gov/pubmed/35208732
http://dx.doi.org/10.3390/microorganisms10020271