Pyrazole and Triazole Derivatives as Mycobacterium tuberculosis UDP-Galactopyranose Inhibitors

UDP-galactopyranose mutase (UGM) is an essential enzyme involved in the bacterial cell wall synthesis, and is not present in mammalian cells. Thus, UGM from Mycobacterium tuberculosis (Mtb) represents a novel and attractive drug target for developing antituberculosis agents. A pyrazole-based compoun...

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Detalles Bibliográficos
Autores principales: Ahmed, Dalia M., Chen, Jeffrey M., Sanders, David A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874540/
https://www.ncbi.nlm.nih.gov/pubmed/35215309
http://dx.doi.org/10.3390/ph15020197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874540/
https://www.ncbi.nlm.nih.gov/pubmed/35215309
http://dx.doi.org/10.3390/ph15020197

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