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PRRSV Non-Structural Proteins Orchestrate Porcine E3 Ubiquitin Ligase RNF122 to Promote PRRSV Proliferation

Ubiquitination plays a major role in immune regulation after viral infection. An alternatively spliced porcine E3 ubiquitin ligase RNF122 promoted PRRSV infection and upregulated in PRRSV-infected PAM cells was identified. We characterized the core promoter of RNF122, located between −550 to −470 bp...

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Detalles Bibliográficos
Autores principales: Sun, Ruiqi, Guo, Yanyu, Li, Xiaoyang, Li, Ruiqiao, Shi, Jingxuan, Tan, Zheng, Zhang, Lilin, Zhang, Lei, Han, Jun, Huang, Jinhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874583/
https://www.ncbi.nlm.nih.gov/pubmed/35216017
http://dx.doi.org/10.3390/v14020424