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Induction of Broad β-lactam Resistance in Achromobacter ruhlandii by Exposure to Ticarcillin Is Primarily Linked to Substitutions in Murein Peptide Ligase Mpl

Achromobacter species are emerging pathogens in cystic fibrosis with inherent resistance to several classes of antimicrobial agents. We exposed strains with wild-type antimicrobial susceptibility to ticarcillin and generated mutants with broad β-lactam resistance. Within the detection limit of the a...

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Detalles Bibliográficos
Autores principales: Andersen, Camilla, Gabrielaite, Migle, Nørskov-Lauritsen, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874589/
https://www.ncbi.nlm.nih.gov/pubmed/35208874
http://dx.doi.org/10.3390/microorganisms10020420