Gremlin-1 and BMP-4 Overexpressed in Osteoarthritis Drive an Osteochondral-Remodeling Program in Osteoblasts and Hypertrophic Chondrocytes

Osteoarthritis (OA) is a whole joint disease characterized by an important remodeling of the osteochondral junction. It includes cartilage mineralization due to chondrocyte hypertrophic differentiation and bone sclerosis. Here, we investigated whether gremlin-1 (Grem-1) and its BMP partners could be...

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Detalles Bibliográficos
Autores principales: Pérez-Lozano, Maria-Luisa, Sudre, Laure, van Eegher, Sandy, Citadelle, Danièle, Pigenet, Audrey, Lafage-Proust, Marie-Helène, Pastoureau, Philippe, De Ceuninck, Frédéric, Berenbaum, Francis, Houard, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874623/
https://www.ncbi.nlm.nih.gov/pubmed/35216203
http://dx.doi.org/10.3390/ijms23042084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874623/
https://www.ncbi.nlm.nih.gov/pubmed/35216203
http://dx.doi.org/10.3390/ijms23042084

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