Cargando…
Correlation of Solubility Thermodynamics of Glibenclamide with Recrystallization and In Vitro Release Profile
The solubility of glibenclamide was evaluated in DMSO, NMP, 1,4-dioxane, PEG 400, Transcutol(®) HP, water, and aqueous mixtures (T = 293.15~323.15 K). It was then recrystallized to solvate and compressed into tablets, of which 30-day stability and dissolution was studied. It had a higher solubility...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874636/ https://www.ncbi.nlm.nih.gov/pubmed/35209181 http://dx.doi.org/10.3390/molecules27041392 |