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Nanoparticles Carrying NF-κB p65-Specific siRNA Alleviate Colitis in Mice by Attenuating NF-κB-Related Protein Expression and Pro-Inflammatory Cellular Mediator Secretion

Ulcerative colitis is a disease that causes inflammation and ulcers in the colon and which is typically recurrent, and NF-κB proteins are important players during disease progression. Here, we assess the impact of silica-coated calcium phosphate nanoparticles carrying encapsulated siRNA against NF-κ...

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Detalles Bibliográficos
Autores principales: Müller, Elena K., Białas, Nataniel, Epple, Matthias, Hilger, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874689/
https://www.ncbi.nlm.nih.gov/pubmed/35214151
http://dx.doi.org/10.3390/pharmaceutics14020419