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New Insights on the Nuclear Functions and Targeting of FAK in Cancer

Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase over-expressed and activated in both adult and pediatric cancers, where it plays important roles in the regulation of pathogenesis and progression of the malignant phenotype. FAK exerts its functions in cancer by two different ways: a kin...

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Detalles Bibliográficos
Autores principales: Pomella, Silvia, Cassandri, Matteo, Braghini, Maria Rita, Marampon, Francesco, Alisi, Anna, Rota, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874710/
https://www.ncbi.nlm.nih.gov/pubmed/35216114
http://dx.doi.org/10.3390/ijms23041998