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Computational Analysis of Mutations in the Receptor-Binding Domain of SARS-CoV-2 Spike and Their Effects on Antibody Binding

Currently, SARS-CoV-2 causing coronavirus disease 2019 (COVID-19) is responsible for one of the most deleterious pandemics of our time. The interaction between the ACE2 receptors at the surface of human cells and the viral Spike (S) protein triggers the infection, making the receptor-binding domain...

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Detalles Bibliográficos
Autores principales: Bozdaganyan, Marine E., Shaitan, Konstantin V., Kirpichnikov, Mikhail P., Sokolova, Olga S., Orekhov, Philipp S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874930/
https://www.ncbi.nlm.nih.gov/pubmed/35215888
http://dx.doi.org/10.3390/v14020295