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Enhancing the Bioavailability and Efficacy of Vismodegib for the Control of Skin Cancer: In Vitro and In Vivo Studies

Skin cancer is the most frequent cancer throughout the world. Vismodegib (VSD) is a hedgehog blocker approved for the prevention and treatment of skin cancer. VSD, however, is poorly bioavailable and has been linked to side effects. This work focused on designing a nano-invasome gel as a vehicle for...

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Detalles Bibliográficos
Autores principales: Salem, Heba F., Gamal, Amr, Saeed, Haitham, Kamal, Marwa, Tulbah, Alaa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874937/
https://www.ncbi.nlm.nih.gov/pubmed/35215238
http://dx.doi.org/10.3390/ph15020126