Chronic Treatment with Metformin Has No Disrupting Effect on the Hepatic Circadian Clock in Mice

Background and Objectives: The antidiabetic agent metformin is known to activate AMP-activated protein kinase (AMPK) in various tissues. Because AMPK can modulate intracellular circadian clocks through regulating the stability of clock components, a single dose of metformin has been reported to affe...

Descripción completa

Detalles Bibliográficos
Autores principales: Hasan, Nazmul, Sugimoto, Koki, Yamada, Koki, Morishige, Jun-ichi, Ushijima, Kentaro, Fujimura, Akio, Nagata, Naoto, Ando, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875024/
https://www.ncbi.nlm.nih.gov/pubmed/35208616
http://dx.doi.org/10.3390/medicina58020293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875024/
https://www.ncbi.nlm.nih.gov/pubmed/35208616
http://dx.doi.org/10.3390/medicina58020293

Ejemplares similares