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Chronic Treatment with Metformin Has No Disrupting Effect on the Hepatic Circadian Clock in Mice

Background and Objectives: The antidiabetic agent metformin is known to activate AMP-activated protein kinase (AMPK) in various tissues. Because AMPK can modulate intracellular circadian clocks through regulating the stability of clock components, a single dose of metformin has been reported to affe...

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Detalles Bibliográficos
Autores principales:	Hasan, Nazmul, Sugimoto, Koki, Yamada, Koki, Morishige, Jun-ichi, Ushijima, Kentaro, Fujimura, Akio, Nagata, Naoto, Ando, Hitoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875024/ https://www.ncbi.nlm.nih.gov/pubmed/35208616 http://dx.doi.org/10.3390/medicina58020293

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