Synergistic Effect of Toceranib and Nanohydroxyapatite as a Drug Delivery Platform—Physicochemical Properties and In Vitro Studies on Mastocytoma Cells

A new combination of Toceranib (Toc; 5-[(5Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(pyrrolidin-1-yl)ethyl]-1H-pyrrole-3-carboxamide) with nanohydroxyapatite (nHAp) was proposed as an antineoplastic drug delivery system. Its physicochemical properties were determine...

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Detalles Bibliográficos
Autores principales: Sobierajska, Paulina, Serwotka-Suszczak, Anna, Targonska, Sara, Szymanski, Damian, Marycz, Krzysztof, Wiglusz, Rafal J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875076/
https://www.ncbi.nlm.nih.gov/pubmed/35216060
http://dx.doi.org/10.3390/ijms23041944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875076/
https://www.ncbi.nlm.nih.gov/pubmed/35216060
http://dx.doi.org/10.3390/ijms23041944

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