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Ex Vivo Model to Assess the Exposure of Patients to Plasticizers from Medical Devices during Pre-CAR-T Cells’ Apheresis

Background: The treatment of relapsed or refractory leukemia remains a major problem. Among the new therapeutic approaches, the use of modified T lymphocytes, called chimeric antigen receptor T cells (CAR-T cells), seems promising. The first step of their preparation is leukapheresis, which involves...

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Detalles Bibliográficos
Autores principales: Lautraite, Raphaëlle, Bernard, Lise, Halle, Pascale, Chennell, Philip, Le Basle, Yoann, Kanold, Justyna, Sautou, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875078/
https://www.ncbi.nlm.nih.gov/pubmed/35202265
http://dx.doi.org/10.3390/toxics10020079