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Improving Antibacterial Activity of a HtrA Protease Inhibitor JO146 against Helicobacter pylori: A Novel Approach Using Microfluidics-Engineered PLGA Nanoparticles

Nanoparticle drug delivery systems have emerged as a promising strategy for overcoming limitations of antimicrobial drugs such as stability, bioavailability, and insufficient exposure to the hard-to-reach bacterial drug targets. Although size is a vital colloidal feature of nanoparticles that govern...

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Detalles Bibliográficos
Autores principales: Hwang, Jimin, Mros, Sonya, Gamble, Allan B., Tyndall, Joel D. A., McDowell, Arlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875321/
https://www.ncbi.nlm.nih.gov/pubmed/35214080
http://dx.doi.org/10.3390/pharmaceutics14020348