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Physiologically Based Pharmacokinetic (PBPK) Model of Gold Nanoparticle-Based Drug Delivery System for Stavudine Biodistribution

Computational modelling has gained attention for evaluating nanoparticle-based drug delivery systems. Physiologically based pharmacokinetic (PBPK) modelling provides a mechanistic approach for evaluating drug biodistribution. The aim of this work is to develop a specific PBPK model to simulate stavu...

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Detalles Bibliográficos
Autores principales: Zazo, Hinojal, Colino, Clara I., Gutiérrez-Millán, Carmen, Cordero, Andres A., Bartneck, Matthias, Lanao, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875329/
https://www.ncbi.nlm.nih.gov/pubmed/35214138
http://dx.doi.org/10.3390/pharmaceutics14020406