Halogenated Dihydropyrrol-2-One Molecules Inhibit Pyocyanin Biosynthesis by Blocking the Pseudomonas Quinolone Signaling System

Quorum-sensing (QS) systems of Pseudomonas aeruginosa are involved in the control of biofilm formation and virulence factor production. The current study evaluated the ability of halogenated dihydropyrrol-2-ones (DHP) (Br (4a), Cl (4b), and F (4c)) and a non-halogenated version (4d) to inhibit the Q...

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Detalles Bibliográficos
Autores principales: Das, Theerthankar, Sabir, Shekh, Chen, Ren, Farrell, Jessica, Kriel, Frederik H., Whiteley, Gregory S., Glasbey, Trevor O., Manos, Jim, Willcox, Mark D. P., Kumar, Naresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875348/
https://www.ncbi.nlm.nih.gov/pubmed/35208954
http://dx.doi.org/10.3390/molecules27041169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875348/
https://www.ncbi.nlm.nih.gov/pubmed/35208954
http://dx.doi.org/10.3390/molecules27041169

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